Echis carinatus snake venom metalloprotease-induced toxicities in mice: Therapeutic intervention by a repurposed drug, Tetraethyl thiuram disulfide (Disulfiram)

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The Effects of Bezoar on the Echis carinatus Snake Venom Poisoning in Mice

The Bezoar, a dense material found in the stomach of wild goat, is widely used against various diseases including snakebite in traditional medicine among the southeast tribes of Iran. This study was performed to evaluate the Bezoar effect on experimental mice receiving 2% and 10% concentrations of natural crude of Echis carinatus snake venom. Various doses of Bezoar (6, 50, 100 & 200 mg/kg/i....

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Partial Purification and Characterization of Anticoagulant Factor from the Snake (Echis Carinatus) Venom

OBJECTIVE(S) Snake venoms contain complex mixture of proteins with biological activities. Some of these proteins affect blood coagulation and platelet function in different ways. Snake venom toxin may serve as a starting material for drug design to combat several pathophysiological problems such as cardiovascular disorders. In the present study, purification of anticoagulation factor from venom...

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the effects of bezoar on the echis carinatus snake venom poisoning in mice

the bezoar, a dense material found in the stomach of wild goat, is widely used against various diseases including snakebite in traditional medicine among the southeast tribes of iran. this study was performed to evaluate the bezoar effect on experimental mice receiving 2% and 10% concentrations of natural crude of echis carinatus snake venom. various doses of bezoar (6, 50, 100 & 200 mg/kg/i.p)...

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antagonistic effects of suramin against the venom of the iranian snake echis carinatus in mice

echis carinatus (saw-scale viper) is one of the most venomous snakes in asia and some parts of the africa with deadly hemotoxic venom. it has been reported that suramin, an antitrypansomiasis drug, can inhibits the toxic effects of some snake venoms. this study was conducted to evaluate the antagonistic effects of suramin against the venom of the iranian snake echis carinatus. adult albino mice...

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ژورنال

عنوان ژورنال: PLOS Neglected Tropical Diseases

سال: 2021

ISSN: 1935-2735

DOI: 10.1371/journal.pntd.0008596